Linear Peptide Synthesis
In accordance with customer demand BioString Inc. can supply high - quality Linear peptides.
With mature peptide synthesis and purification methods, especially SPPS method and liquid phase synthesis method, we provide customers with high quality peptides:
- Purity: crude ,70%, 75%, 80%, 85%, 90%, 95%, 98%, 99% .
- Desalination and Salt transfer : according to customers’ requirements, we can do TFA salt treatment, can also convert to acetate.
- Delivery time: within 30 amino acids, about 2-3 weeks, urgent order, 1-2 weeks.
- Quality control: providing MS, HPLC and COA reports documents of each peptide with delivery free.
- After-sales service: problems submitted in 1-2 weeks, we provide free-issue retest ,and refund for
- Unqualified products. Ineligible goods retesting in 1-3 month free,and store samples1-2 weeks.
Long Peptide Synthesis
BioString provides long peptide synthesis service within the length of 150 amino acids. When peptide sequence is too long, it often appears that lack of residues, difficulty of condensation of amino acids and so on in the process of peptide synthesis. We have developed three schemes which effectively improve reaction on base of these problems.
- Microwave synthesis: for some amino acids hard to condensate in the process of synthesis, we used microwave synthesiswhich is a significant effect method and greatly reduced the reaction time.
- Fragment synthesis method: when it is difficult to synthesize certain peptides with conventional synthesis method, we will alsosynthesize a few amino acids as a fragment, then as a whole condensate to the peptide chain. This method can solve manyproblems existing in the synthesis.
- 3.Hydrazine synthesis: A synthesis method to connect the peptides through forming amide bond with selective chemical reaction between N-terminal Cys peptide and C-terminal peptide acyl hydrazine in the solid phase synthesis.According to the position of Cys in peptide, we divide the entirepeptide chain into a plurality of sequences to synthesize separately, eventually to obtain the target peptide using liquid phase condensation reaction,which significantly improvesthe purity of the final product, widely used in the synthesis of long peptide containing Cys .
With mature peptide synthesis technology, Bankpeptide can fast design effective synthesis scheme and provide better service according to the customers requests, which is our constant pursuit.
BioString can provides a wide rang of peptides with various modifications according to customers’ requires!
- Phosphorylation of Ser, Tyr and Thr modified peptides: we provide a single phosphorylation and multi phosphorylated peptide services. Now we have been able to provide four phosphorylated sites modified peptides.
- Fluorescent labeling ,such as 5 (6) -FAM, FITC, Cy5, Rhodamine B, PNA, EDNAS/dabcyl etc.
Which is our representative technology and already quite mature.
- Biotin, Lys (biotin) : Biotin is one part of the vitamin B2, and biotin, Lys (biotin) modified peptides are also often purchased by customers. We offer a biotin modified peptide that already has a success rate of nearly 100%.
- Disulfide Bridge: disulfide bridge bond plays an important role in the stability of protein structure.we have been able to provide customers up to four disulfide bridges in one peptide .
- Isotope labeling (C13, N15 labeling): isotope labeled peptides are mainly used in medical and biological fields at higher prices, In order to meet the needs of customers, we accept micrograms isotope labeling peptide customization.
- Other special amino acid modification: for example, D amino acids, amino acid derivatives, aliphatic carboxylic acidsand so on, which all in our acceptable customization.
Confidential Agreement will be signed upon request by customer to protect sensitive information such as peptide sequence information.